Title: Top 10 Hotels in Mayo River from $57 - Competitive Prices | Expedia.com [Mayo River Travel Guide](https://expedia.com/Mayo-River.dx553248635976006279)[Vacation Rentals in Mayo River](https://expedia.com/Mayo-River-Vacation-Rentals.d553248635976006279.Travel-Guide-VacationRentals)[Flights to Mayo River](https://expedia.com/Cheap-Flights-To-Mayo-River.d553248635976006279.Travel-Guide-Flights)[Car Rentals in Mayo River](https://expedia.com/Car-Rentals-In-Mayo-River.d553248635976006279.Car-Rental-Guide)[Mayo River Vacation Packages](https://expedia.com/Mayo-River.d553248635976006279.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mayo River Pet-friendly [](https://www.expedia.com/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&amenities=PETS) Great for families [](https://www.expedia.com/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&travelerType=family_friendly) Pool [](https://www.expedia.com/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&amenities=POOL) Cabins [](https://www.expedia.com/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&lodging=CABIN) Farm [](https://www.expedia.com/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&lodging=AGRITOURISM) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&amenities=HOT_TUB) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&lodging=APARTMENT) Cottages [](https://www.expedia.com/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2026-03-01&d1=2026-03-01&endDate=2026-03-03&d2=2026-03-03&lodging=COTTAGE) ## Check prices for these dates Tonight [Feb 15 - Feb 16](https://www.expedia.com/Hotel-Search?regionId=553248635976006279&startDate=2026-02-15&endDate=2026-02-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 16 - Feb 17](https://www.expedia.com/Hotel-Search?regionId=553248635976006279&startDate=2026-02-16&endDate=2026-02-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=553248635976006279&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=553248635976006279&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mayo River hotels ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/6af9837a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/e5d1371d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/dc25ed12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, deep soaking tub, free toiletries, hair dryer](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/fb9092c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Eden [](https://www.expedia.com/Reidsville-Hotels-Baymont-By-Wyndham-Eden.h570926.Hotel-Information) Eden 8.6/10 Excellent (574 reviews) "Clean rooms, friendly staff and close to everything " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karrie $81 nightly $90 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Reidsville-Hotels-Baymont-By-Wyndham-Eden.h570926.Hotel-Information) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/012d74f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/a3e0a9a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/a762e12d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/33d9301a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Martinsville [](https://www.expedia.com/Martinsville-Hotels-Baymont-By-Wyndham-Martinsville.h665072.Hotel-Information) Martinsville 6.8/10 (628 reviews) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela $107 nightly $120 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Martinsville-Hotels-Baymont-By-Wyndham-Martinsville.h665072.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/f228f500.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/fc4390ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/83b78e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/27086093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Eden [](https://www.expedia.com/Reidsville-Hotels-Hampton-Inn-Eden.h42735.Hotel-Information) Eden 8.6/10 Excellent (440 reviews) "The staff was very friendly, and the place was very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shyquam $110 nightly $123 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Reidsville-Hotels-Hampton-Inn-Eden.h42735.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/3001752c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/a26d27a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch LCD TV with digital channels, TV](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/1a577c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/37620728.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Floyd [](https://www.expedia.com/Floyd-Hotels-Hotel-Floyd.h8986854.Hotel-Information) Floyd 9.6/10 Exceptional (494 reviews) "Enjoyed our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hania $110 nightly $121 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Floyd-Hotels-Hotel-Floyd.h8986854.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/9e55a796.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/de713ac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/9f72338d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/ee448a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scottish Inns Collinsville-Martinville [](https://www.expedia.com/Martinsville-Hotels-Scottish-Inns-Collinsville-Martinville.h154773.Hotel-Information) Collinsville 6.8/10 (282 reviews) "The room was very clean and the staff very friendly. It's an older establishment but spic and span clean!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James $51 nightly $57 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Martinsville-Hotels-Scottish-Inns-Collinsville-Martinville.h154773.Hotel-Information) ![Standard Room, Refrigerator & Microwave (2 full beds Smoking) | Bed sheets](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/9b6faa06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/796ec9c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/e9f8e260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/0412020c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eden Inn Motel [](https://www.expedia.com/Reidsville-Hotels-Eden-Inn-Motel.h12764520.Hotel-Information) Eden 6.6/10 (192 reviews) "Staff was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Austin $62 nightly $70 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Reidsville-Hotels-Eden-Inn-Motel.h12764520.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/9373a79c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/053c1303.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/6e4e4f38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/23224694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Martinsville [](https://www.expedia.com/Martinsville-Hotels-Econo-Lodge.h12704.Hotel-Information) Martinsville 6.4/10 (482 reviews) "Great upgrade " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittany $61 nightly $67 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Martinsville-Hotels-Econo-Lodge.h12704.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/96000000/95840000/95832200/95832103/78ac86ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/96000000/95840000/95832200/95832103/d7bc649f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95840000/95832200/95832103/a6854b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room | Living area](https://images.trvl-media.com/lodging/96000000/95840000/95832200/95832103/15d9d221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn [](https://www.expedia.com/Ridgeway-Hotels-4520-Greensboro-Rd.h95832103.Hotel-Information) Ridgeway 6.0/10 (65 reviews) "Good sheap room friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tyler $59 nightly $66 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Ridgeway-Hotels-4520-Greensboro-Rd.h95832103.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101230000/101227000/101226990/b508e4ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/102000000/101230000/101227000/101226990/ccbf7682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/102000000/101230000/101227000/101226990/0877213b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Studio, Non Smoking | Living area | 42-inch LED TV with cable channels](https://images.trvl-media.com/lodging/102000000/101230000/101227000/101226990/c2376f02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax Inn [](https://www.expedia.com/Collinsville-Hotels-Relax-Inn.h101226990.Hotel-Information) Collinsville 5.6/10 (32 reviews) "Courteous staff comfy bed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lisa $54 nightly $60 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Collinsville-Hotels-Relax-Inn.h101226990.Hotel-Information) ![Economy Double Room | Individually furnished, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/96000000/95010000/95002100/95002016/1b3f29b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95010000/95002100/95002016/e8bbcbd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95010000/95002100/95002016/ad5a388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/96000000/95010000/95002100/95002016/382b0e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Virginian Motel [](https://www.expedia.com/Stuart-Hotels-Virginian-Motel.h95002016.Hotel-Information) Stuart 6.2/10 (57 reviews) "Very nice rooms, and staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heidi $70 nightly $79 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Stuart-Hotels-Virginian-Motel.h95002016.Hotel-Information) ![Basic Room | Premium bedding, free WiFi](https://images.trvl-media.com/lodging/97000000/96170000/96163300/96163271/965638dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/97000000/96170000/96163300/96163271/bf928be5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Room | Premium bedding, free WiFi](https://images.trvl-media.com/lodging/97000000/96170000/96163300/96163271/a8e34c99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Room | Bathroom | Towels](https://images.trvl-media.com/lodging/97000000/96170000/96163300/96163271/415cfd97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### RIDGEWAY INN [](https://www.expedia.com/Ridgeway-Hotels-RIDGEWAY-INN.h96163271.Hotel-Information) Ridgeway 4.8/10 (10 reviews) "Food and stores near by" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ellisah $67 nightly $75 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Ridgeway-Hotels-RIDGEWAY-INN.h96163271.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/0f261a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/35d81c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, soundproofing, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/63ddbb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/04e1ce3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Ridgeway Martinsville Area [](https://www.expedia.com/Martinsville-Hotels-Travelodge-By-Wyndham-Ridgeway-Martinsville-Area.h10801.Hotel-Information) Ridgeway 6.6/10 (193 reviews) "Room was great Peaceful stay Had no towels but management bought me some I enjoyed myself " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ann $67 nightly $75 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Martinsville-Hotels-Travelodge-By-Wyndham-Ridgeway-Martinsville-Area.h10801.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/c2d0654a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/94618658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, 1 King Bed, Non Smoking | Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/75661a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/df0b8433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Martinsville [](https://www.expedia.com/Martinsville-Hotels-Hampton-Inn-Martinsville.h43095.Hotel-Information) Martinsville 9.0/10 Wonderful (517 reviews) "Yes everything was great!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa $183 nightly $204 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Martinsville-Hotels-Hampton-Inn-Martinsville.h43095.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/17000000/16110000/16104100/16104080/53b70a18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Seaside Room | Lounge](https://images.trvl-media.com/lodging/17000000/16110000/16104100/16104080/e00bedbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/17000000/16110000/16104100/16104080/96be5127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Seaside Room | Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/17000000/16110000/16104100/16104080/2e8ed635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hunter House Bed and Breakfast [](https://www.expedia.com/Reidsville-Hotels-Hunter-House-Bed-And-Breakfast.h16104080.Hotel-Information) Madison 9.4/10 Exceptional (37 reviews) "Everything was just as advertised and the hosts were extremely nice and very accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald $173 nightly $190 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Reidsville-Hotels-Hunter-House-Bed-And-Breakfast.h16104080.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/101000000/100150000/100143400/100143353/e64831c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/101000000/100150000/100143400/100143353/5f79a23d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/101000000/100150000/100143400/100143353/6cec13e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Honeymoon Suite | Living area](https://images.trvl-media.com/lodging/101000000/100150000/100143400/100143353/5be0834e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moonlight Manor Bed and Breakfast [](https://www.expedia.com/Floyd-Hotels-Moonlight-Manor-Bed-And-Breakfast.h100143353.Hotel-Information) Floyd 9.8/10 Exceptional (43 reviews) "Great host and breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Min $146 nightly $161 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Floyd-Hotels-Moonlight-Manor-Bed-And-Breakfast.h100143353.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/92000000/91330000/91324500/91324436/af5afe61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/92000000/91330000/91324500/91324436/w1200h799x0y1-80d962fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/92000000/91330000/91324500/91324436/w1199h799x1y1-6f66c031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/92000000/91330000/91324500/91324436/63dda0e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Oakdale Inn [](https://www.expedia.com/Martinsville-Hotels-The-Oakdale-Inn.h91324436.Hotel-Information) Martinsville 10/10 Exceptional (22 reviews) "Great stay! Would definitely recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doug $152 nightly $170 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Martinsville-Hotels-The-Oakdale-Inn.h91324436.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112770000/112765400/112765345/a2002bd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | Private spa tub](https://images.trvl-media.com/lodging/113000000/112770000/112765400/112765345/c2dd2c5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112770000/112765400/112765345/5bca12d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | 5 bedrooms, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/113000000/112770000/112765400/112765345/ae38011e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### King Bed Pet Friendly BBQ Grill Peaceful [](https://www.expedia.com/Madison-Hotels-King-Bed-Pet-Friendly-BBQ-Grill-Peaceful.h112765345.Hotel-Information) Madison 8.0/10 Very Good (1 review) $314 nightly $345 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Madison-Hotels-King-Bed-Pet-Friendly-BBQ-Grill-Peaceful.h112765345.Hotel-Information) ![Tree House, 1 King Bed (Cooper's Hawk, Adults Only) | View from room](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/96761cd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/d9e4023f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/84ebd106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/296f749d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Primland, Auberge Collection [](https://www.expedia.com/Meadows-Of-Dan-Hotels-The-Lodge-At-Primland.h3633184.Hotel-Information) Meadows Of Dan 9.0/10 Wonderful (26 reviews) "The resort is an experience. The staff were helpful and genuine. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melinda $401 nightly $450 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/Meadows-Of-Dan-Hotels-The-Lodge-At-Primland.h3633184.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-01&endDate=2026-03-02®ionId=553248635976006279&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_553248635976006279) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMayo-River-Hotels.d553248635976006279.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMayo-River-Hotels.d553248635976006279.Travel-Guide-Hotels) ## Stay near popular Virginias attractions ### Reynolds Homestead You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forest or visit its spas. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561864249) ## Learn more about Mayo River Head to sights like Reynolds Homestead as you discover the local area in Mayo River. [See all hotels in Mayo River](https://www.expedia.com/Hotel-Search?startDate=2026-03-01&endDate=2026-03-02&adults=2®ionId=553248635976006279) ![The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.](https://images.trvl-media.com/place/553248621561864249/54558157-d5bc-4ba5-a77d-f9a917492c5a.jpg?impolicy=fcrop&w=899&h=675&p=1&q=high) Photo by Ed Mayfield ## Top Mayo River Hotel Reviews ![Econo Lodge Martinsville](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/9373a79c_y.jpg) ### Econo Lodge Martinsville 10/10 Excellent "Great upgrade " [](https://expedia.com/Martinsville-Hotels-Econo-Lodge.h12704.Hotel-Information) ![Hampton Inn Martinsville](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/c2d0654a_y.jpg) ### Hampton Inn Martinsville 10/10 Excellent "Yes everything was great!!! " [](https://expedia.com/Martinsville-Hotels-Hampton-Inn-Martinsville.h43095.Hotel-Information) ![Hampton Inn Eden](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/f228f500_y.jpg) ### Hampton Inn Eden 10/10 Excellent "The room and the eating area were both very clean. The staff is nice and the breakfast was good. " [](https://expedia.com/Reidsville-Hotels-Hampton-Inn-Eden.h42735.Hotel-Information) ![Baymont by Wyndham Eden](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/34cebbf3_y.jpg) ### Baymont by Wyndham Eden 10/10 Excellent "Clean and safe. " [](https://expedia.com/Reidsville-Hotels-Baymont-By-Wyndham-Eden.h570926.Hotel-Information) ![Travelodge by Wyndham Ridgeway Martinsville Area](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/35d81c0c_y.jpg) ### Travelodge by Wyndham Ridgeway Martinsville Area 10/10 Excellent "Room was great Peaceful stay Had no towels but management bought me some I enjoyed myself " [](https://expedia.com/Martinsville-Hotels-Travelodge-By-Wyndham-Ridgeway-Martinsville-Area.h10801.Hotel-Information) ![Eden Inn Motel](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/796ec9c2_y.jpg) ### Eden Inn Motel 10/10 Excellent "Staff was amazing " [](https://expedia.com/Reidsville-Hotels-Eden-Inn-Motel.h12764520.Hotel-Information) ![Scottish Inns Collinsville-Martinville](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/ee448a9a_y.jpg) ### Scottish Inns Collinsville-Martinville 10/10 Excellent "The room was very clean and the staff very friendly. It's an older establishment but spic and span clean!" [](https://expedia.com/Martinsville-Hotels-Scottish-Inns-Collinsville-Martinville.h154773.Hotel-Information) ![Travel Inn](https://images.trvl-media.com/lodging/96000000/95840000/95832200/95832103/d7bc649f_y.jpg) ### Travel Inn 10/10 Excellent "Good sheap room friendly staff" [](https://expedia.com/Ridgeway-Hotels-4520-Greensboro-Rd.h95832103.Hotel-Information) ![Comfort Inn Martinsville](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/5a1d33a7_y.jpg) ### Comfort Inn Martinsville 10/10 Excellent "Nice stay" [](https://expedia.com/Martinsville-Hotels-Baymont-By-Wyndham-Martinsville.h665072.Hotel-Information) ## More cheap stays in Mayo River ![Scottish Inns Collinsville-Martinville](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/ee448a9a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Scottish Inns Collinsville-Martinville 2357 Virginia Ave Collinsville VA $51 nightly $57 total Feb 23 - Feb 24 Total with taxes and fees 6.8/10 (281 reviews) [](https://expedia.com/Martinsville-Hotels-Scottish-Inns-Collinsville-Martinville.h154773.Hotel-Information) ![Travelodge by Wyndham Ridgeway Martinsville Area](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/35d81c0c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Travelodge by Wyndham Ridgeway Martinsville Area 3841 Greensboro Rd Ridgeway VA $67 nightly $75 total Mar 1 - Mar 2 Total with taxes and fees 6.6/10 (193 reviews) [](https://expedia.com/Martinsville-Hotels-Travelodge-By-Wyndham-Ridgeway-Martinsville-Area.h10801.Hotel-Information) ![Baymont by Wyndham Eden](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/34cebbf3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Eden 716 Linden Dr Eden NC $81 nightly $90 total Mar 1 - Mar 2 Total with taxes and fees 8.4/10 Very Good! (572 reviews) [](https://expedia.com/Reidsville-Hotels-Baymont-By-Wyndham-Eden.h570926.Hotel-Information) ![Hotel Floyd](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/e5c62df7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Floyd 300 Rick Lewis Way Floyd VA $110 nightly $121 total Feb 16 - Feb 17 Total with taxes and fees 9.6/10 Exceptional! (493 reviews) [](https://expedia.com/Floyd-Hotels-Hotel-Floyd.h8986854.Hotel-Information) ![Hampton Inn Eden](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/f228f500_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Eden 724 S Van Buren Rd Eden NC $110 nightly $123 total Feb 22 - Feb 23 Total with taxes and fees 8.6/10 Excellent! (440 reviews) [](https://expedia.com/Reidsville-Hotels-Hampton-Inn-Eden.h42735.Hotel-Information) ![Hampton Inn Martinsville](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/c2d0654a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Martinsville 50 Hampton Dr Martinsville VA $183 nightly $204 total Feb 22 - Feb 23 Total with taxes and fees 8.8/10 Excellent! (517 reviews) [](https://expedia.com/Martinsville-Hotels-Hampton-Inn-Martinsville.h43095.Hotel-Information) ## Hotels in Mayo River with star-rating ![5 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25559/c6e0103a_z.jpg) 5 Star Hotels 1 properties [](https://expedia.com/5Star-Mayo-River-Hotels.s50-0-d553248635976006279.Travel-Guide-Filter-Hotels) ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.com/4Star-Mayo-River-Hotels.s40-0-d553248635976006279.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 22 properties [](https://expedia.com/3Star-Mayo-River-Hotels.s30-0-d553248635976006279.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 37 properties [](https://expedia.com/2Star-Mayo-River-Hotels.s20-0-d553248635976006279.Travel-Guide-Filter-Hotels) ## Explore a world of travel with Expedia - 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